GlycoEnzDB

General Information

Gene Symbol:

DPM2

Protein name:

Dolichol phosphate-mannose biosynthesis regulatory protein

Enzyme Class:

CAZy Family:

E.C. No:

Reaction (SNFG):

No reaction

→

Reaction (IUBMB):

No specified reaction.

About

* This is an essential regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex, which includes DPM1 and DPM3.
* This protein is also part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of GlcNAc UDP-GlcNAc to phosphatidylinositol during first step of GPI biosynthesis

Related Pathway

KEGG ORTHOLOGY:

K09658

KEGG Pathway:

ko00510 ko00563 ko01100

Reactome:

R-HSA-162699

Related Database

Organism:

Homo sapiens

Uniprot:

O94777

NCBI GeneID:

8818

GlyMap GeneID:

8818

DNA_RefSeq:

NM_003863.3

Protein_RefSeq:

NP_003854.1

BRENDA:

Kinetic info.

OMIM number:

603564

GeneCards database:

DPM2

Enzyme Specificity

Glycan Type:

N_linked

Compartment:

ER

Substrate:

No reaction(-CHAR)

Product:

(-CHAR)

Simulation Parameters

Mechaelis-Menten parameters (suggested)
Vm: (pmol/cell • hr) Km: (pM)
Relative conc of enzymes in compartment.(sum will be normalized to 1)

ER	Cis-	Medial-	Trans-	TGN

Expression Data {ref. 5} Source from NCBI gene database

Expression data are collected from NCBI gene database

Cancer Cell Line Encyclopedia {ref. 13} Source from Cancer Cell Line Encyclopedia database