GlycoEnzDB
The Comprehensive Glyco-enzyme Database
| GPF-Fuc [cyto] | → | GPF-Fuc [Golgi] |
* Transports only GDP-Fuc (synthesized in cytoplasm) to the Golgi lumen
* Golgi fucosylation was strongly impaired in SLC35C1-deficient patients and knockout mouse, fucosylation in the ER was not extensively affected. Thus, there may be other fucose transporters in ER
| ER | Cis- | Medial- | Trans- | TGN |
|---|---|---|---|---|
| SLC35C1/hsa-miR-6825-5p |
|---|
| miRNA Target | Site Type | Pos. | Context Score | Frac. | Wt. Context | Frac. | Conserved | Quality |
|---|---|---|---|---|---|---|---|---|
|
5'...UUCUCCCAGUUCUA
CCUCCCCA
... 3' UACGACUGAGGUGU GGAGGGG U |
8mer | 857-864 | -0.307 | 90.0 | -0.245 | 86.0 | noncon | |
|
5'...AGGGUCAUUAACAU
CCUCCCC
C... 3' UACGACUGAGGUGU GGAGGGG U |
7mer-m8 | 710-716 | -0.242 | 81.0 | -0.194 | 78.0 | noncon | |
|
5'...UCCCCAGAAGCCUU
CCUCCCCA
... 3' UACGACUGAGGUGU GGAGGGG U |
8mer | 873-880 | -0.233 | 79.0 | -0.187 | 77.0 | noncon |