GlyClass

GlycoEnzDB
Comprehensive glycoEnzyme database and dynamic pathway generation

Description: The GlycoEnzDB is a manually curated glycoEnzyme database, primarily focused on humans. It covers 390 enzymes across 28 pathway maps. Facilities are also available to create custom glycosylation reaction pathways using experimental data in SBML format and for pathway simulation
Contacts: Sriram Neelamegham (neel@buffalo.edu), Yusen Zhou (yusenzho@buffalo.edu) or Ted Groth (tgroth@buffalo.edu).

GlycoEnzDB
Create glycosylation pathway
Custom database generation
Instructions/Reference
 
Pathway Map
ARSK



General Information
Gene Symbol:   
ARSK
Protein name:   
Arylsulfatase K
Enzyme Class:   
CAZy Family:   
E.C. No:   
3.1.6.*
Organs:   
Reaction (SNFG):   

GlcA(b1-4 [2S]) → GlcA(b1-4)
Reaction (IUBMB):   
No specified reaction.
About

• Exhibits glucuronate-2-sulfatase activity, needed for the degradation of heparan sulfate, chondroitin sulfate and dermatan sulfate.

Related Pathway
KEGG ORTHOLOGY:   
KEGG Pathway:   
No Record 
Reactome:   
R-HSA-1660662
Related Database
Organism:   
Homo sapiens
Uniprot:   
Q6UWY0 
NCBI GeneID:   
153642
GlyMap GeneID:   
153642
DNA aRefSeq:   
NM_198150.2 
Protein RefSeq:   
NP_937793.1 
BRENDA:   
Kinetic info.
OMIM number:   
610011
GeneCards database:   
ARSK
Enzyme Specificity
Glycan Type:  
     GAG
Compartment:  
     
Substrate:  
     GlcA(b1-4 [2S])
Product:  
     GlcA(b1-4)
Simulation Parameters
Mechaelis-Menten parameters (suggested)
VM:       (pmol/cell • hr)       KM:       (pM)
Relative conc of enzymes in compartment.(sum will be normalized to 1)
ER Cis- Medial- Trans- TGN










Expression Data in Tissue {ref. 5} Source from NCBI gene database
No expression data available.
Expression Data in Cells
No expression data available.
Transcription factor {ref. 10}
No high degree of confidence data