Gene Details: FPGT
1 / 1
General Information
Gene Name: FPGT (Fucose-1-phosphate guanylyltransferase)
Synonym: GFPP
Short Names:
Alternative Names: GDP-L-fucose diphosphorylase;GDP-L-fucose pyrophosphorylase;
Notes:
- Fucose 1-phosphate guanylytranferase transfers GTP to fucose, resulting in GDP-fucose. Is an essential precursor for glycosylation via fucose salvage pathway.
Description from Dr.Glyco-GPT:
Warning: LLMs can generate factually incorrect information, as they simply predict the next word based on training data. Always verify LLM output by cross-checking with reliable sources!
Catalytic Activity
Reaction and Disease Links
EC # (IUBMB):
2.7.7.30
Brenda:
2.7.7.30
OMIM:
603609
KEGG: 8790
Rhea:
13549
Reactome :
R-HSA-6787639
Transcript levels (Cell lines and Single cell data) URL
CRISPR-knockout
CRISPR-activation
CRISPR-inactivation
Transcription factor-gene relationship (details at glycoTF page)
Top 10 TFs
| TF | Score |
|---|---|
| TCF25 | 0.204363 |
| UBE2I | 0.202386 |
| SSU72 | 0.201971 |
| SUMO1 | 0.199515 |
| YY1 | 0.195441 |
| NCOR1 | 0.194566 |
| GTF2A2 | 0.194264 |
| PHB2 | 0.191878 |
| FXR1 | 0.191383 |
| XRCC5 | 0.190532 |
Licensing: CC BY 4.0. You are fee to copy, redistribute, remix, transform and build upon all material, except for textbook figures from the Essentials.