Gene Details: G6PC1

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General Information

Gene Name: G6PC1 (Glucose-6-phosphatase catalytic subunit 1)
Synonym: G6PC
Short Names:
Alternative Names: Glucose-6-phosphatase;Glucose-6-phosphatase alpha;
HGNC: 4056
NCBI: 2538
UniProt: P35575
CAZy:
GlyGen: P35575

Notes:

Description from Dr.Glyco-GPT:

Warning: LLMs can generate factually incorrect information, as they simply predict the next word based on training data. Always verify LLM output by cross-checking with reliable sources!

Catalytic Activity

Reaction Image

Reaction and Disease Links

EC # (IUBMB): 3.1.3.9
Brenda: 3.1.3.9
OMIM: 232200 613742
KEGG: 2538
Rhea: 16689
Reactome : R-HSA-3274531 R-HSA-70263 R-HSA-9615017

Transcript levels (Cell lines and Single cell data) URL

CRISPR-knockout

CRISPR-activation

CRISPR-inactivation

Transcription factor-gene relationship (details at glycoTF page)


Top 10 TFs

TF Score
NR1H4 0.021478
HNF4A 0.021474
CAT 0.018170
PPARA 0.016709
HNF4G 0.014010
TEAD1 0.013871
MAF 0.012688
SOX6 0.011895
NFIB 0.011834
PAX8 0.011803
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