Gene Details: GALK1
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General Information
Gene Name: GALK1 (Galactokinase)
Synonym: GALK
Short Names:
Alternative Names: Galactose kinase;
Notes:
- Phosphorylates galactose to form galactose 1 phosphate. Involved in the sugar nucleotide synthesis of UDP-galactose.
- Important enzyme for salvage pathway to obtain UDP-Gal via Leloir pathway.
Description from Dr.Glyco-GPT:
Warning: LLMs can generate factually incorrect information, as they simply predict the next word based on training data. Always verify LLM output by cross-checking with reliable sources!
Catalytic Activity

Reaction and Disease Links
EC # (IUBMB):
2.7.1.6
Brenda:
2.7.1.6
KEGG: 2584
Rhea:
13553
Transcript levels (Cell lines and Single cell data) URL
CRISPR-knockout

CRISPR-activation

CRISPR-inactivation

Transcription factor-gene relationship (details at glycoTF page)
Top 10 TFs
TF | Score |
---|---|
TCF25 | 0.815893 |
UBE2I | 0.811762 |
SSU72 | 0.807348 |
XRCC5 | 0.789363 |
YY1 | 0.782183 |
HNRNPK | 0.779267 |
RBM39 | 0.777615 |
SON | 0.772928 |
PCBP1 | 0.770117 |
SUMO1 | 0.766212 |
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