Gene Details: GALK2
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General Information
Gene Name: GALK2 (N-acetylgalactosamine kinase)
Synonym: GK2
Short Names:
Alternative Names: GalNAc kinase;Galactokinase 2;
Notes:
- Phosphorylates Nacetylgalactosamine to form Nacetylgalactosamine 1 phosphate. Involved in the sugar nucleotide synthesis of UDP-galactose.
- Important enzyme for salvage pathway to obtain UDP-GalNAc via Leloir pathway.
Description from Dr.Glyco-GPT:
Warning: LLMs can generate factually incorrect information, as they simply predict the next word based on training data. Always verify LLM output by cross-checking with reliable sources!
Catalytic Activity
Reaction and Disease Links
EC # (IUBMB):
2.7.1.157
Brenda:
2.7.1.157
OMIM:
137028
KEGG: 2585
Rhea:
12617
Transcript levels (Cell lines and Single cell data) URL
CRISPR-knockout
CRISPR-activation
CRISPR-inactivation
Transcription factor-gene relationship (details at glycoTF page)
Top 10 TFs
| TF | Score |
|---|---|
| TCF25 | 0.577611 |
| UBE2I | 0.568654 |
| SSU72 | 0.560257 |
| YY1 | 0.558751 |
| XRCC5 | 0.556663 |
| SON | 0.552369 |
| HNRNPK | 0.549967 |
| RBM39 | 0.546556 |
| NCOR1 | 0.546049 |
| SNRNP70 | 0.539464 |
Licensing: CC BY 4.0. You are fee to copy, redistribute, remix, transform and build upon all material, except for textbook figures from the Essentials.