Gene Details: ALG10
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General Information
Gene Name: ALG10 (Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase)
Synonym: ALG10A
Short Names:
Alternative Names: Alpha-1,2-glucosyltransferase ALG10-A;Alpha-2-glucosyltransferase ALG10-A;Asparagine-linked glycosylation protein 10 homolog A;
Notes:
- Dol-P-Glc is formed from UDP-Glc using ALG5.
- Three Glc residues are then transferred from Dol-P-Glc to the LLO using ER-resident ALG6 [α(1,3)GlcT], ALG8 [α(1,3)GlcT] and ALG10 [α(1,2)GlcT].
Description from Dr.Glyco-GPT:
Warning: LLMs can generate factually incorrect information, as they simply predict the next word based on training data. Always verify LLM output by cross-checking with reliable sources!
Catalytic Activity
Reaction and Disease Links
EC # (IUBMB):
2.4.1.256
Brenda:
2.4.1.256
OMIM:
618355
KEGG: 84920
Reactome :
R-HSA-446193
Transcript levels (Cell lines and Single cell data) URL
CRISPR-knockout
CRISPR-activation
CRISPR-inactivation
Transcription factor-gene relationship (details at glycoTF page)
Top 10 TFs
| TF | Score |
|---|---|
| UBE2I | 0.093253 |
| SSU72 | 0.092484 |
| SNRNP70 | 0.091756 |
| TCF25 | 0.090912 |
| NCOR1 | 0.090170 |
| NONO | 0.089381 |
| SUMO1 | 0.089154 |
| EWSR1 | 0.088156 |
| YY1 | 0.087393 |
| FXR1 | 0.087382 |
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