Synthesis of Dolichol-P-P-GlcNAc

2

Man

9

Glc

3

Adapted from Chapter 9, Figure 3. Essentials of Glycobiology, Fourth Edition

Cold Spring Harbor Laboratory Press. Copyright 2022 by The Consortium of Glycobiology Editors, La Jolla, California. All rights reserved.

RPN1

RPN2

DDOST

DAD1

STT3A

OSTA

OSTB

RPN1

RPN2

DDOST

DAD1

STT3B

DOLK SRD5A3

DOLPP1

DPAGT1 ALG13

/14

ALG1 ALG2 ALG2 ALG11

ALG11

PMM2

GPI MPI

GMPPA

GMPPB

ALG3

DPM1,

DPM2,

DPM3

ALG5

ALG6

ALG9

ALG9

ALG12

ALG8

ALG10