Gene Details: ALG13
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General Information
Gene Name: ALG13 (UDP-N-acetylglucosamine transferase subunit ALG13)
Synonym: CXorf45
Short Names:
Alternative Names: Asparagine-linked glycosylation 13 homolog;Glycosyltransferase 28 domain-containing protein 1;
Notes:
- Alg13/Alg14 are part of a heterodimer that transfers second GlcNAc from UDP-GlcNAc to generate Dol-PP-GlcNAc2.
- Cells lacking these activities grow slowly, and mutations in Alg13 leads to CDG-1r.
Description from Dr.Glyco-GPT:
Warning: LLMs can generate factually incorrect information, as they simply predict the next word based on training data. Always verify LLM output by cross-checking with reliable sources!
Catalytic Activity
Reaction and Disease Links
EC # (IUBMB):
2.4.1.141
KEGG: 79868
Transcript levels (Cell lines and Single cell data) URL
CRISPR-knockout
CRISPR-activation
CRISPR-inactivation
Transcription factor-gene relationship (details at glycoTF page)
Top 10 TFs
| TF | Score |
|---|---|
| SON | 1.401245 |
| RBM39 | 1.398485 |
| HNRNPK | 1.378285 |
| FUS | 1.360070 |
| SRSF3 | 1.348859 |
| TCF25 | 1.341430 |
| SFPQ | 1.338618 |
| PCBP2 | 1.329578 |
| SUMO2 | 1.324889 |
| HNRNPH1 | 1.322693 |
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