Gene Details: ALG14
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General Information
Gene Name: ALG14 (UDP-N-acetylglucosamine transferase subunit ALG14)
Synonym:
Short Names:
Alternative Names: Asparagine-linked glycosylation 14 homolog;
Notes:
- Alg13/Alg14 are part of a heterodimer that transfers second GlcNAc from UDP-GlcNAc to generate Dol-PP-GlcNAc2.
- Cells lacking these activities grow slowly, and mutations in Alg13 leads to CDG-1r.
Description from Dr.Glyco-GPT:
Warning: LLMs can generate factually incorrect information, as they simply predict the next word based on training data. Always verify LLM output by cross-checking with reliable sources!
Catalytic Activity
Reaction and Disease Links
KEGG: 199857
Transcript levels (Cell lines and Single cell data) URL
CRISPR-knockout
CRISPR-activation
CRISPR-inactivation
Transcription factor-gene relationship (details at glycoTF page)
Top 10 TFs
| TF | Score |
|---|---|
| UBE2I | 0.427442 |
| SSU72 | 0.424241 |
| TCF25 | 0.419684 |
| SUMO1 | 0.419499 |
| GTF2A2 | 0.413369 |
| YY1 | 0.412933 |
| SNRNP70 | 0.410674 |
| PHB2 | 0.409865 |
| NCOR1 | 0.400467 |
| NONO | 0.399487 |
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